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See a video file for Professor Kim's research (The second presentation titled as "creation of interactive protein domain assemblies")

CREATION OF INTERACTIVE PROTEIN DOMAIN ASSEMBLIES
Research in Kim's lab has been focused on engineering of proteins for the creation of "interactive" protein domain assemblies. A complex engineering/science problem requires not only simple integration of multi-functionalities of proteins but also creation of "cross-talking" between functional protein domains. For example, one can design a stimulus-responsive molecular actuator using two protein domains responsible for stimulus recognition and structural changes. However, design of protein domain assemblies with inter-functionalities is highly challenging due to the complex nature of proteins and the intricate linkage between structures and functions. Capitalizing on our expertise in the design of functional proteins and control of protein properties, we have worked, since Prof. Kim joined NYU-Poly in 2006, on development of interactive protein domain assemblies aimed at solving the two most significant engineering/science problems currently recognized. The long-term goal of our research is to create a cont rollable protein network in the context of multi-scaled artificial or natural systems, such as molecular constructs formed by other biopolymers, cellular assemblies, and an entire organism.


Proteins of various functions and structures

http://publications.nigms.nih.gov/structlife/images/ch1_thoughts.jpg




Creation of interactive protein domain assemblies for various applications                An analogy to the progress of media (single medium to interactive media)